Microsatellite DNA instability and loss of heterozygosity in bronchial asthma
نویسندگان
چکیده
منابع مشابه
Microsatellite DNA instability and loss of heterozygosity in bronchial asthma.
Genetic alterations, such as loss of heterozygosity (LOH) or microsatellite instability (MI), have been reported in both malignant and benign disorders. In order to identify loci of deoxyribonucleic acid (DNA) mutation in asthma, MI and LOH were studied in sputum cells. DNA was extracted from cells in the sputum and blood cells of 22 patients with moderate asthma. Cells were analysed for MI and...
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objective(s): variation in microsatellite sequences that are dispersed in the genome has been linked to a deficiency in cellular mismatch repair system and defects in several genes of this system are involved in carcinogenesis. our aim in this study was to illustrate microsatellite dna alteration in esophageal cancer. materials and methods: dna was extracted from formalin fixed paraffin embedde...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2003
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.03.00010503